Compatible hard drives for Synology RS3621RPxs
33 drives are on Synology's official compatibility list for the RS3621RPxs. Read from synology.com, list refreshed 2026-11-03.
Intel Xeon D-1531 · 6C/12T · DDR4 ECC UDIMM 8 GB · Broadwellnk
| CPU | Intel Xeon D-1531 — 6 cores, 12 threads |
| Memory (as shipped) | DDR4 ECC UDIMM 8 GB |
| Platform | Broadwellnk · x86_64 — package arch used by Synology's package center |
This Synology line keeps the stricter policy: unlisted drives are accepted for migration from an existing system only — new storage pools and caches require drives from the official list below. Full policy guide →
October 2026 — C3RB3R ransomware campaign. Is the RS3621RPxs at risk? Not by model — by DSM build. If this unit runs DSM below 7.4-90075 / 7.3.2-86009-4 / 7.2.2-72806-9 / 7.2.1-69057-12 (or any DSM 6.x), and its admin interface is reachable from the internet, it is exposed to the ongoing C3RB3R campaign. Check Control Panel → Info Center, update, then run the 12-step lockdown. Files already encrypted with .L0CK3D? Recovery guide — don't reboot first.
Capacity range on the official list
Full RS3621RPxs compatibility list
Grouped by part number; Max shows the largest capacity Synology lists. Filter by brand, line or capacity:
| Drive | Brand | Series | Line | Type | Max listed |
|---|---|---|---|---|---|
| HAT5320-24T | Synology | HAT5320 | Enterprise | 3.5" SATA HDD | 24 TB |
| HAT5310-20T | Synology | HAT5310 | Enterprise | 3.5" SATA HDD | 20 TB |
| HAT5320-20T | Synology | HAT5320 | Enterprise | 3.5" SATA HDD | 20 TB |
| HAT5310-18T | Synology | HAT5310 | Enterprise | 3.5" SATA HDD | 18 TB |
| HAT5300-16T | Synology | HAT5300 | Enterprise | 3.5" SATA HDD | 16 TB |
| HAT5310-16T | Synology | HAT5310 | Enterprise | 3.5" SATA HDD | 16 TB |
| HAT5300-12T | Synology | HAT5300 | Enterprise | 3.5" SATA HDD | 12 TB |
| HAT5300-8T | Synology | HAT5300 | Enterprise | 3.5" SATA HDD | 8 TB |
| HAT5310-8T | Synology | HAT5310 | Enterprise | 3.5" SATA HDD | 8 TB |
| HAT5320-8T | Synology | HAT5320 | Enterprise | 3.5" SATA HDD | 8 TB |
| SAT5210-7000G | Synology | SAT5210 | Enterprise | 2.5" SATA SSD | 7 TB |
| HAT5300-4T | Synology | HAT5300 | Enterprise | 3.5" SATA HDD | 4 TB |
| HAT5320-4T | Synology | HAT5320 | Enterprise | 3.5" SATA HDD | 4 TB |
| HUS726T4TALE6L4 - 0B36040 | Western Digital | Ultrastar DC HC310 | Enterprise | 3.5" SATA HDD | 4 TB |
| MG04ACA400E | Toshiba | MG04ACA**** | Enterprise | 3.5" SATA HDD | 4 TB |
| ST4000NM002A | Seagate | Exos 7E8 | Enterprise | 3.5" SATA HDD | 4 TB |
| SAT5200-3840G | Synology | SAT5200 | Enterprise | 2.5" SATA SSD | 3.84 TB |
| SAT5210-3840G | Synology | SAT5210 | Enterprise | 2.5" SATA SSD | 3.84 TB |
| SAT5220-3840G | Synology | SAT5220 | Enterprise | 2.5" SATA SSD | 3.84 TB |
| SAT5221-3840G | Synology | SAT5221 | Enterprise | 2.5" SATA SSD | 3.84 TB |
| MG04ACA300E | Toshiba | MG04ACA**** | Enterprise | 3.5" SATA HDD | 3 TB |
| SAT5200-1920G | Synology | SAT5200 | Enterprise | 2.5" SATA SSD | 1.92 TB |
| SAT5210-1920G | Synology | SAT5210 | Enterprise | 2.5" SATA SSD | 1.92 TB |
| SAT5220-1920G | Synology | SAT5220 | Enterprise | 2.5" SATA SSD | 1.92 TB |
| SAT5221-1920G | Synology | SAT5221 | Enterprise | 2.5" SATA SSD | 1.92 TB |
| SAT5200-960G | Synology | SAT5200 | Enterprise | 2.5" SATA SSD | 960 GB |
| SAT5210-960G | Synology | SAT5210 | Enterprise | 2.5" SATA SSD | 960 GB |
| SAT5220-960G | Synology | SAT5220 | Enterprise | 2.5" SATA SSD | 960 GB |
| SAT5221-960G | Synology | SAT5221 | Enterprise | 2.5" SATA SSD | 960 GB |
| SAT5200-480G | Synology | SAT5200 | Enterprise | 2.5" SATA SSD | 480 GB |
| SAT5210-480G | Synology | SAT5210 | Enterprise | 2.5" SATA SSD | 480 GB |
| SAT5220-480G | Synology | SAT5220 | Enterprise | 2.5" SATA SSD | 480 GB |
| SAT5221-480G | Synology | SAT5221 | Enterprise | 2.5" SATA SSD | 480 GB |
Going big on the RS3621RPxs?
At the top of the capacity range only enterprise lines are listed. They are built for sustained 7200RPM writes and 24/7 RAID duty — the right choice for a full-bay build: